Science.

Mitochondria.

Fragmentation and positioning.

We ask how oxidative stress and damage are interpreted by the mitochondria and which proteins actuate the changes in mitochondrial network and positioning in response to stress.

Publications:

  1. Structural and functional...in press

  2. Loss of TRPML1...

  3. Mitochondrial aberrations...

Zinc transporters.

Evolution and function.

We ask whether it is possible to predict the function and localization of zinc transporters using their evolutionary histories.

Publications:

  1. Zn2+ efflux...

  2. Zinc-dependent...

Lysosomal exocytosis.

Roles in toxicity and cancer.

We ask whether it is possible to modulate the activity of cytotoxic drugs by regulating the lysosomal exocytosis.

Publications:

  1. Copper-dependent...

  2. Biphasic regulation...

  3. Brief exposure...

  4. Zn2+ efflux...